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74 SARCOMAS OF BONE AND SOFT TISSUES

74 SARCOMAS OF BONE AND SOFT TISSUES Harrison’s Manual of Medicine 74 SARCOMAS OF BONE AND SOFT TISSUES Soft Tissue Sarcomas Bone Sarcomas Osteosarcoma Chondrosarcoma Ewing’s Sarcoma Bibliography SOFT TISSUE SARCOMAS INCIDENCE AND ETIOLOGY   About 6400 cases are diagnosed each year in the U.S. 60% arise in extremities, lower:upper = 3:1; 30% on the the trunk, […]

48 COMMON DISORDERS OF THE EYE

48 COMMON DISORDERS OF THE EYE Harrison’s Manual of Medicine 48 COMMON DISORDERS OF THE EYE Clinical Assessment Specific Disorders Bibliography Clinical Assessment The history and examination permit accurate diagnosis of most eye disorders, without resort to laboratory or imaging studies. The essential ocular exam includes assessment of the visual acuity, pupil reactions, eye movements, […]

25 OVERT MANIFESTATIONS OF RENAL DISEASE

25 OVERT MANIFESTATIONS OF RENAL DISEASE Harrison’s Manual of Medicine 25 OVERT MANIFESTATIONS OF RENAL DISEASE Abnormalities of Renal Function Abnormalities of Urine Volume Abnormalities of Urine Composition Bibliography ABNORMALITIES OF RENAL FUNCTION Azotemia is the retention of nitrogenous waste products excreted by the kidney. Increased levels of blood urea nitrogen (BUN) (>30 mg/dL) and […]

23 JAUNDICE AND EVALUATION OF LIVER FUNCTION

23 JAUNDICE AND EVALUATION OF LIVER FUNCTION Harrison’s Manual of Medicine 23 JAUNDICE AND EVALUATION OF LIVER FUNCTION Jaundice Hepatomegaly Blood Tests of Liver Function Hepatobiliary Imaging Procedures Bibliography JAUNDICE DEFINITION   Yellow skin pigmentation caused by elevation in serum bilirubin level (also termed icterus); often more easily discernible in sclerae. Scleral icterus become clinically evident at […]

The Gist of Emergency Medicine

The Gist of Emergency Medicine Michael O. Hebb MD,CCFP(EM),DABEM Woodlawn Medical Clinic 110 Woodlawn Road Dartmouth, Nova Scotia Canada B2W 2S8 Copyright 1998 [Please Note] [TOC] Table of Contents Preface The Mnemonic & Preamble The Management Guide The Short Form of the Management Guide Significant Reminders CPR -Electrolytes -Acid Base Cardiac Arrythmias & ACLS Drugs […]

Pathology and Genetics of Tumours of the Digestive System

World Health Organization Classification of Tumours International Agency for Research on Cancer (IARC) Pathology and Genetics of Tumours of the Digestive System Edited by Stanley R. Hamilton Lauri A. Aaltonen IARCPress Lyon, 2000 WHO OMS Editors Clinical Editor Editorial Assistance Layout Illustrations Printed by Publisher Stanley R. Hamilton, M.D. Lauri A. Aaltonen, M.D., Ph.D. René […]

CHAPTER 86 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF LYMPHOCYTE AND PLASMA CELL DISORDERS

CHAPTER 86 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF LYMPHOCYTE AND PLASMA CELL DISORDERS Williams Hematology CHAPTER 86 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF LYMPHOCYTE AND PLASMA CELL DISORDERS THOMAS J. KIPPS Classification Clinical Manifestations B-Lymphocyte Disorders T-Lymphocyte Disorders Chapter References This chapter outlines the major categories of lymphocyte and plasma cell disorders. Such disorders can be sorted […]

CHAPTER 85 FUNCTIONS OF NATURAL KILLER CELLS

CHAPTER 85 FUNCTIONS OF NATURAL KILLER CELLS Williams Hematology CHAPTER 85 FUNCTIONS OF NATURAL KILLER CELLS GIORGIO TRINCHIERI LEWIS L. LANIER Identification and Definition of Natural Killer Cells Definition Morphology Origin and Tissue Distribution Mechanisms of Natural Killer Cell Functions Cell-Mediated Cytotoxicity Production of Cytokines Physiologic Roles of Natural Killer Cells Natural Resistance Regulation of […]

CHAPTER 76 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF DISORDERS OF MONOCYTES AND MACROPHAGES

CHAPTER 76 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF DISORDERS OF MONOCYTES AND MACROPHAGES Williams Hematology CHAPTER 76 CLASSIFICATION AND CLINICAL MANIFESTATIONS OF DISORDERS OF MONOCYTES AND MACROPHAGES MARSHALL A. LICHTMAN Classification Monocytopenia Monocytosis and Histiocytosis Qualitative Disorders of Monocytes Clinical Manifestations of Monocyte Disorders Monocytopenia or Monocyte Dysfunction Monocytosis Histiocytosis Chapter References Disorders that result in […]

CHAPTER 75 PRODUCTION, DISTRIBUTION, AND FATE OF MONOCYTES AND MACROPHAGES

CHAPTER 75 PRODUCTION, DISTRIBUTION, AND FATE OF MONOCYTES AND MACROPHAGES Williams Hematology CHAPTER 75 PRODUCTION, DISTRIBUTION, AND FATE OF MONOCYTES AND MACROPHAGES TOMAS GANZ ROBERT I. LEHRER Identification and Kinetic Studies of Monocytes and Macrophages Phylogeny and Ontogeny of Macrophages Tissue Distribution of Monocytes and Macrophages The Development of Monocytes in the Marrow Kinetics of […]