187 MULTIPLE SCLEROSIS (MS) Harrison’s Manual of Medicine 187 MULTIPLE SCLEROSIS (MS) Clinical Manifestations Physical Examination Disease Course Laboratory Findings Bibliography Characterized by chronic inflammation and selective destruction of CNS myelin; peripheral nervous system is spared. Pathologically, the multifocal scarred lesions of MS are termed plaques. Etiology is thought to be autoimmune, with susceptibility determined […]