Archive | December 2011

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CHAPTER 64 MORPHOLOGY OF NEUTROPHILS, EOSINOPHILS, AND BASOPHILS

CHAPTER 64 MORPHOLOGY OF NEUTROPHILS, EOSINOPHILS, AND BASOPHILS Williams Hematology CHAPTER 64 MORPHOLOGY OF NEUTROPHILS, EOSINOPHILS, AND BASOPHILS DOROTHY FORD BAINTON Neutrophils Light Microscopy and Peroxidase Histochemistry Electron Microscopy and Peroxidase Cytochemistry Other Cytoplasmic Changes During Maturation Contents of Neutrophil Granules Pathologic Alterations of Granules Eosinophils Light Microscopy of Eosinophils in Marrow and Blood Films […]

CHAPTER 63 HEREDITARY AND ACQUIRED SIDEROBLASTIC ANEMIAS

CHAPTER 63 HEREDITARY AND ACQUIRED SIDEROBLASTIC ANEMIAS Williams Hematology CHAPTER 63 HEREDITARY AND ACQUIRED SIDEROBLASTIC ANEMIAS ERNEST BEUTLER Definition and History Etiology and Pathogenesis Morphologic Aspects. the Sideroblasts Pathogenesis Clinical and Laboratory Features Primary Acquired Sideroblastic Anemia Secondary Acquired Sideroblastic Anemia Hereditary Sideroblastic Anemia Treatment Chapter References Sideroblastic anemias are characterized by the presence of […]

CHAPTER 62 THE HEMATOLOGIC ASPECTS OF PORPHYRIA

CHAPTER 62 THE HEMATOLOGIC ASPECTS OF PORPHYRIA Williams Hematology CHAPTER 62 THE HEMATOLOGIC ASPECTS OF PORPHYRIA SHIGERU SASSA Definition and History Etiology and Pathogenesis Heme Control of Heme Synthesis in the Liver and Erythroid Cells Erythropoietic Porphyrias Congenital Erythropoietic Porphyria (CEP) Erythropoietic Protoporphyria Hepatic Porphyrias Acute Hepatic Porphyrias Chronic Hepatic Porphyrias Chapter References The porphyrias […]

CHAPTER 61 POLYCYTHEMIA

CHAPTER 61 POLYCYTHEMIA Williams Hematology CHAPTER 61 POLYCYTHEMIA ERNEST BEUTLER Definition and History Etiology and Pathogenesis Polycythemia Vera Secondary Polycythemia Clinical Features Polycythemia Vera Secondary Polycythemia Laboratory Features Polycythemia Vera Secondary Polycythemia Differential Diagnosis Polycythemia Vera Secondary Polycythemia Spurious Polycythemia Therapy, Course, and Prognosis Polycythemia Vera Secondary Polycythemia Chapter References Polycythemia is characterized by an […]

CHAPTER 60 HYPERSPLENISM AND HYPOSPLENISM

CHAPTER 60 HYPERSPLENISM AND HYPOSPLENISM Williams Hematology CHAPTER 60 HYPERSPLENISM AND HYPOSPLENISM ALLAN J. ERSLEV Hypersplenism History and Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis Hyposplenism Definition Etiology and Pathogenesis Clinical Features Laboratory Features Therapy, Course, and Prognosis Chapter References The normal spleen shares with other tissues a number of […]

CHAPTER 59 ACUTE BLOOD LOSS ANEMIA

CHAPTER 59 ACUTE BLOOD LOSS ANEMIA Williams Hematology CHAPTER 59 ACUTE BLOOD LOSS ANEMIA ROBERT S. HILLMAN CHAIM HERSHKO Volume Loss and Replacement Clinical Manifestations Replacement Therapy Red Cell Loss and Replacement Clinical Manifestations Erythropoietic Response Therapy Homologous Blood Transfusion Maximizing Red Cell Output Chapter References The clinical manifestations of acute blood volume loss reflect […]

CHAPTER 58 ALLOIMMUNE HEMOLYTIC DISEASE OF THE NEWBORN

CHAPTER 58 ALLOIMMUNE HEMOLYTIC DISEASE OF THE NEWBORN Williams Hematology CHAPTER 58 ALLOIMMUNE HEMOLYTIC DISEASE OF THE NEWBORN JAYASHREE RAMASETHU NAOMI L.C. LUBAN Definition and History Etiology and Pathogenesis Causative Antibodies RH Hemolytic Disease ABO Hemolytic Disease Hemolytic Disease Due to Other Red Cell Antibodies Clinical Features Anemia Jaundice Other Clinical Features Obstetric History Laboratory […]