Leave a comment

Ethyldichloroarsine

Ethyldichloroarsine (ED)

Diagnosis

1.
Dermal and ocular toxicity

2.
Erythema, eye pain, photophobia, shivering, thirst, muscle weakness, hemolysis with hemoglobinuria and jaundice

3.
Nasal and throat toxcity < 1 min

4.
Odor of gas: fruity, but biting & irritating

5.
Garlicky breath odor
History

1.
Made by Germans in 1918
Pathophysiology

1.
Rapid hydrolysis; short persistency

2.
Stable in steel

3.
Liberates arsine gas

4.
Attacks brass at 50 deg C

5.
Destructive to rubber & plastics

6.
Lethal dose: 3,000-5,000 mg/min/m3

7.
Skin absorbtion: 100,000 mg/min/m3
Decontamination

1.
Protective mask

2.
Impermeable protective clothing

3.
Hypochlorite 0.5% soln used on skin

4.
Live steam or alkaline solns (e.g. sodium hydroxide) used to decontaminate closed spaces
Treatment

1.
Morphine sulphate for pain

2.
Diphenhydramine for pruritis

3.
Silver sulfadiazine 1% to prevent skin infection

4.
Monitor for hemolysis-blood transfusions may be needed
Disposition

1.
Admit if hemolysis present

2.
Notify CDC & local health dept
Military Detection/Treatment Kits
(See Chemical Agent ID/Detection)

1.
M256A1, MINICAMS, M18A2, M21, M90, M93A1, CAM, DAAMS, M8, and M9 paper

* Material is taken from the PEPID database
* Copyrighted material – All Rights Reserved
* For more information visit http://www.pepid.com

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: